Weekly Chest CasesArchive of Old Cases

Case No : 610 Date 2009-07-06

  • Courtesy of Inyoung Youn, Semin Chong, Jae Seung Seo / Chung-Ang University College of Medicine, Seoul, South Korea.
  • Age/Sex 67 / M
  • Chief ComplaintDyspnea on exertion for 6 months, fever, chilling for 3 days
  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5

Fig 1

Diagnosis With Brief Discussion

Diagnosis
COP (Cryptogenic organizing pneumonia)
Radiologic Findings
Chest radiograph (Figure 1) showed multifocal patchy increased opacities in the both lungs. Lung window setting of the chest CT (Figure 2-5) scan showed subpleural , segmental or peribronchovascular ground glass opacities in both lungs. There were also combined fibrosis and traction bronchiectasis and emphysemas in both lungs.
He underwent video-assisted thoracic surgery biopsy at areas of ground glass opacities in right superior segment of RLL and posterior segment of RUL. One week later, he complained of more worsening dyspnea with progression of the lesion on serial follow up chest radiographs. Follow up chest radiograph (Figure 6, answer) and chest CT scan ( Figure 7-10, answer) showed more progression of the ground glass opacities and more fibrosis / parenchymal distorsion in both upper lobes than prior study. Ten days later after the biopsy, pathologic results showed fibroblast plug in the bronchiole with extension to the alveolar ducts (Figure 11). On the results of the clinical, radiologic and pathologic findings, we diagnosed cryptogenic organizing pneumonia in this case. After steroid therapy, his symptoms and chest radiographic findings have improved.
Brief Review
Please refer to case 63, case 110, case 230, case 286, and case 294.

References
Keywords
Lung, Idiopathic interstitial pneumonia, IIP,

No. of Applicants : 89

▶ Correct Answer : 4/89,  4.5%
  • - POPOVO HOSPITAL , Bulgaria VLADISLAV RUSINOV
  • - SRI RAVI NURSING HOME,,WARANGAL , India PAVAN KUMAR VODITHALA
  • - jaslok hospital & research centre mumbai , India JAINENDRA JAIN
  • - bmcri , India sanjeev choudri
▶ Correct Answer as Differential Diagnosis : 19/89,  21.3%
  • - Shinsegye Rad Clinic, Daegu , Korea (South) Gi Beom Kim
  • - Univ. of Miami/Jackson Memorial , United States mantosh rattan
  • - Vital Imaging Centre, Mumbai,India , India Ganesh Agrawal
  • - Samsung Medical Center , Korea (South) Eun Kim
  • - Kashan University of Medical Sciences, kashan , Iran Ebrahim Razi
  • - PingTung Christian Hospital ,China Medical University ,Taiwan,R.O.C. , Taiwan Jun Jun Yeh
  • - Diskapi Yildirim Beyazit Hospital, Ankara , Turkey Meric Tuzun
  • - clinique de rochefort , France viviane pages
  • - Hangang Sacred Heart Hospital , Korea (South) Eil Seong Lee
  • - kims,narkatpally , India k bhaskar
  • - NASA SCANS , India RAKESH BHATIA
  • - Hopital du SacrCoeur , Canada Abraham Bohadana
  • - Mallinckrodt Institute of Radiology , United States Naganathan Mani
  • - Deptt of Radiodiagnosis & Imaging, PGIMER chandigarh , India Ram Galwa
  • - Medical College Chest Hospital,Thrissur,Kerala , India Raveendran TK
  • - NOUR EL-ISLAM RADIOLOGY CENTER , Egypt Elsayed Mousa
  • - clinique de SAVOIE , France, Metropolitan gay-depassier philippe
  • - PITTWATER RADIOLOGY , Australia Saurabh Khandelwal
  • - PITTWATER RADIOLOGY , Australia Julie Arora
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